Introduction to MiAIRR


One of the primary initiatives of the Adaptive Immune Receptor Repertoire (AIRR) Community has been to develop a set of metadata standards for the submission of AIRR sequencing datasets. This work has been carried out by the AIRR Community Minimal Standards Working Group. In order to support reproducibility, standard quality control, and data deposition in a common repository, the AIRR Community has agreed to six high-level data sets that will guide the publication, curation and sharing of AIRR-Seq data and metadata: Study and subject, sample collection, sample processing and sequencing, raw sequences, processing of sequence data, and processed AIRR sequences. The detailed data elements within these sets are defined here.

A scheme of the MiAIRR data set and data elements

Schema of MiAIRR data sets and the individual data elements of each set.


  • NCBI-based - see this document
  • AIRR Common Repositories - in development


[Rubelt_2017]Rubelt F et al. AIRR Community Recommendations for Sharing Immune Repertoire Sequencing Data. Nat Immunol 18:1274 (2017) DOI: 10.1038/ni.3873
[Breden_2017]Breden F et al. Reproducibility and Reuse of Adaptive Immune Receptor Repertoire Data. Front Immunol 8:1418 (2017) DOI: 10.3389/fimmu.2017.01418
[Zenodo_1185414]Release archive of the AIRR Standards repository. (2015-2018) DOI: 10.5281/zenodo.1185414