Name Type Attributes Definition subject_id string required, identifier, nullable "Subject ID assigned by submitter, unique within study. If possible, a persistent subject ID linked to an INSDC or similar repository study should be used. " synthetic boolean required TRUE for libraries in which the diversity has been synthetically generated (e.g. phage display) species :ref:`Ontology ` required Binomial designation of subject's species organism :ref:`Ontology ` DEPRECATED Binomial designation of subject's species sex string required, nullable Biological sex of subject age :ref:`TimeInterval ` required, nullable "Age of subject expressed as a time interval. If singular time point then min == max in the time interval. " age_event string required, nullable "Event in the study schedule to which `Age` refers. For NCBI BioSample this MUST be `sampling`. For other implementations submitters need to be aware that there is currently no mechanism to encode to potential delta between `Age event` and `Sample collection time`, hence the chosen events should be in temporal proximity. " age_min number DEPRECATED age_max number DEPRECATED age_unit :ref:`Ontology ` DEPRECATED ancestry_population :ref:`Ontology ` required, nullable Broad geographic origin of ancestry (continent) location_birth :ref:`Ontology ` optional, nullable Self-reported location of birth of the subject, preferred granularity is country-level ethnicity string required, nullable Ethnic group of subject (defined as cultural/language-based membership) race string required, nullable Racial group of subject (as defined by NIH) strain_name string required, nullable Non-human designation of the strain or breed of animal used linked_subjects string required, nullable Subject ID to which `Relation type` refers link_type string required, nullable Relation between subject and `linked_subjects`, can be genetic or environmental (e.g.exposure) diagnosis array of :ref:`Diagnosis ` optional Diagnosis information for subject genotype :ref:`SubjectGenotype ` optional, nullable